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Crystalline Lens Subluxation

What is Crystalline Lens Subluxation?
Crystalline lens subluxation is a disruption of the fibers that hold the lens in place inside the eye. When this occurs, the lens is de-centered from its normal position, but still remains visible through the pupil.

What causes Crystalline Lens Subluxation?
The most common cause is trauma. However, there are other ocular and systemic conditions that can cause Crystalline Lens Subluxation as well. These include, but are not limited to:

  • Pseudoexfoliation Syndrome: this is when the fibers that hold the lens in place are weak, and pieces of them can break off and attach to the lens
  • Significant, or hypermature cataract
  • Marfan Syndrome: a systemic condition with associated heart problems
  • Homocystinuria: a systemic condition with frequent mental and skeletal issues as well

Symptoms of Crystalline Lens Subluxation
While Crystalline Lens Subluxation can occur in anyone, these three profiles are most prone: significant blunt trauma to the eye or head; systemic conditions such as Marfan's syndrome, homocystinuria, hyperlysinuria, familial ectopia lentis, sulfite oxidase deficiency, Weill-Marchesani syndrome, aniridia and Ehlers-Danlos syndrome; hypermature cataract.

The most common symptoms of Crystalline Lens Subluxation are decreased vision, and double vision that remains even when covering one eye (known as monocular diplopia).

Treatment of Crystalline Lens Subluxation
Extraction of a dislocated lens can be difficult, so a subluxated lens itself is not sufficient reason to pursue surgery. If there are no symptoms associated with lens subluxation, the condition is monitored. If symptoms arise, the most common treatment is removal of the lens, and often a replacement of the lens with a prosthetic (similar to cataract surgery).