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STERILE CORNEAL INFILTRATES

What are Sterile Corneal Infiltrates?

Sterile Corneal Infiltrates are an acute immune response to corneal damage and epithelial breakdown most often caused by contact lens wear. Sterile Corneal Infiltrates appear as gray-white lesions on the cornea. It is more common for infiltrates to appear individually, but they can also appear in groups. Sterile Corneal Infiltrates can affect one or both eyes. After the infiltrate has healed, a corneal scar may form.

What causes Sterile Corneal Infiltrates?

Sterile Corneal Infiltrates are associated with contact lens wear, the type of contact lens worn, the wearing schedule, contact lens hygiene, and contact lens case contamination by bacteria. Studies have shown that extended wear soft contact lens patients are 2.3 times more likely to develop Sterile Corneal Infiltrates as compared to gas permeable hard contact lens wearers. Daily wear soft contact lens patients are 1.56 times more likely to develop Sterile Corneal Infiltrates as compared tSterile Corneal Infiltrateso gas permeable hard contact lens wearers.

  • contact lens wear   
  • non-compliance to manufacturer's lens replacement schedule
  • overnight contact lens wear
  • non-compliance to care schedules
  • poor contact lens or lens case hygiene
  • hypersensitivity to contact lens material
  • hypersensitivity to contact lens solutions or re-wetting drops
  • reaction to preservatives found in contact lens solutions and re-wetting drops
  • dry eye syndrome
  • collagen vascular diseases

Symptoms of Sterile Corneal Infiltrates:

  • normal to blurred vision
  • absence of pain to mild pain
  • little to no ocular irritation

Symptoms of Sterile Corneal Infiltrates are wide ranging, making it difficult for a patient to determine the severity of the condition.

 

Treatment of Sterile Corneal Infiltrates:

  • discontinue contact lens wear until advised otherwise by your eye doctor
  • topical antibiotics
  • topical steroids